求是理学论坛第十三场�Prof. Sauvage
报告题目：From copper-complexed interlocking compounds to molecular machines
报告人：Prof. Jean-Pierre Sauvage
报告时间：
报告地点：化学楼，教八 –107
报告内容简介：Catenanes and rotaxanes have attracted much interest in molecular chemistry, first as pure synthetic challenges and, more recently, as components of functional materials. Since the beginning of the 80s', these compounds are relatively easily accessible, thanks to the various routes which have been proposed by several research laboratories and which are based on the use of templates (transition metals or organic templates). In recent years, two-dimensional interlocking arrays have been designed and elaborated. Here again, the transition metal (copper(I)) plays an essential role : several metal centres are combined with several organic fragments so as to lead to a multicomponent assembly similar to a small membrane fragment, the various organic components being threaded or interlocked with one another instead of being covalently linked. Separately, the field of artificial molecular machines has experienced a spectacular development, in relation to molecular devices at the nanometric level or as mimics of biological motors. These systems are multicomponent assemblies undergoing large-amplitude geometrical changes or leading to the locomotion of one of the components, under the action of an external stimulus. A recent example is that of a [3]rotaxane acting as an adjustable receptor. The compound is also able to behave as a chemically-driven "molecular press" : It can accommodate and compress given substrates located between two mobile porphyrinic plates. The most recent system consists of two bis-macrocycles threaded by two rods. The[4]rotaxane obtained also incorporates two porphyrinic "plates". In the course of the last five years, we have also been much interested in endocyclic but non sterically hindering chelates. These compounds are based on carefully designed 3,3'- biisoquinoline derivatives. Some of them have even been incorporated into macrocyclic compounds. A particularly efficient and fast moving molecular "shuttle" based on such a chelate has been made and investigated. A rapidly shuttling copper-complexed [2]rotaxane with three different chelating groups in its axis has been synthesised, which allows fast motion of the mobile copper-complexed ring over a large distance (> 20 Å).
报告人简介：1967 Engineer from the Ecole Nationale Supérieure de Chimie de